Kaolin and Pectin Medications
Kaolin and pectin mixtures are locally acting and are considered a type of over-the-counter antidiarrheal medication. Â They work by adsorbing any irritating substances and soothing the intestinal mucosa.
The mixture of kaolin and pectin is not absorbed orally and does not get distributed throughout the body. However, it is excreted in the feces.
Kaolin and pectin are adsorbents that bind with bacteria, toxins, and other irritants in the intestinal mucosa. Â Pectin works by decreasing the pH in the intestinal lumen and provides a soothing effect on irritated mucosa.
Kaolin and pectin are useful in relieving mild to moderate acute diarrhea and can be used when the exact cause of diarrhea is unknown.
It is important to keep in mind that kaolin and pectin can hinder the absorption of digoxin and other drugs in the intestinal lumen when given simultaneously; therefore changing the timing of certain medications and not giving at the same time is of utmost importance.
Overall, kaolin and pectin are well tolerated but they can sometimes cause constipation in the elderly and other debilitated patients.
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Adverse reactions
The following are important to note when observing individuals that use antidiarrheal medications:
- Nausea and vomiting
- Abdominal discomfort or distention
- Drowsiness and fatigue
- Central nervous system depression
- Tachycardia
- Paralytic ileus – absent or reduced peristaltic movements in the intestine
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